Kleiderer-Pezold Professor of Biochemistry; Director, W.M. Keck Center for Transgene Research

Frank Castellino

Education:
B.S., University of Scranton, 1964
M.S., University of Iowa, 1966
Ph.D., University of Iowa, 1968

Recent Articles:

  • Balsara RD, Dang A, Donahue DL, Snow T, Castellino FJ (2015). "Conantokin-G attenuates the detrimental effects of NMDAR hyperactivity in an ischemic rat model of stroke. PLoS One 10(3):e0122840. doi:10.1371/journal.pone.0122840. PMID:25822337.
  • Kunda S, Yuan Y, Balsara RD, Zajicek J, Castellino F (2015). "Hydroxyproline-induced helical disruption in conantokin Rl-B affects subunit-selective antagonistic activities toward NMDA receptors." J. Biol. Chem. 290(29):18156-18172.  doi:10.1074/jbc.M115.65034.  PMID:26048991.
  • Chandrahas V, Glinton K, Liang Z, Ploplis VA, Castellino FJ (2015). "Direct host plasminogen binding to bacterial surface M-protein in Pattern D strains of Streptococcus pyogenes is required for activation by its natural coinherited SK2b." J. Biol. Chem. 290(30):18833-18842.  doi:10.1074/jbc.M115.655365. PMID:26070561.
  • Bao Y-J, Liang Z, Mayfield JA, Lee SW, Ploplis VA, Castellino FJ (2015). "CovRS regulated transcriptome analysis of a hypervirulent M23 strain of Group A Streptococcus pyogenes offers new insights on virulence determinants." J. Bacteriol. 197(19):3191-3205. doi: 10.1128/JB.00511-15. PMID:26216843.

Office: 230 Raclin-Carmichael
Department webpage: http://chemistry.nd.edu/faculty/detail/fcastell/
Email: fcastell@nd.edu